Ac Tiva Tion of M Yos in Lig Ht C

Question

Ac tiva tion of m yos in lig ht c ha in k ina se (M LC K) in s m oo th m us cle sh ou ld
A) Increase smooth m uscle force
B) R ela x s m oo th m us cle
C) Increase the [Ca2+] in smooth m uscle cells
D) D ep ola rize the sm oo th m us cle ce lls
E) Increase Ca2+ release from the SR

Accepted Answer

Activation of myosin light chain kinase (MLCK) in smooth muscle leads to phosphorylation of the myosin light chain, which enables myosin to interact with actin filaments, thereby increasing smooth muscle force.