What is the Consequence of Methylation of DNA Sequences Called

Question

What is the consequence of methylation of DNA sequences called CpG islands?
A) active transcription
B) transcription repression
C) recruitment of chromosome-remodeling complex
D) transcriptional stalling
E) insulator sequence formation

Accepted Answer

Methylation of CpG islands typically leads to transcription repression by preventing the binding of transcription factors and recruiting proteins that compact the chromatin, making it less accessible for transcription.