Oncogenic Mutations in H-Ras are Most Often the Result Of

Question

Oncogenic mutations in H-Ras are most often the result of
A)Point mutations resulting in a premature stop codon.
B)Point mutations that change the protein's structure and result in its constitutive activation.
C)Insertion of extra bases in exon 1 of the gene.
D)Frameshift mutations.
E)None of the above.

Accepted Answer

Oncogenic mutations in H-Ras are most often point mutations in the gene that change the protein's structure and result in its constitutive activation. This means that the mutated H-Ras protein is always "on" and signaling to the cell to divide and grow, which can lead to the development of cancer.