When Experimental Mice are Treated with DMBA and TPA to Induce

Question

When experimental mice are treated with DMBA and TPA to induce the formation of papillomas,TPA
A)Serves as the initiating agent.
B)Serves as the promoting agent.
C)Must be administered multiple times in order for papillomas to form.
D)B and C.
E)None of the above.

Accepted Answer

TPA serves as the promoting agent in the formation of papillomas when experimental mice are treated with DMBA and TPA. Additionally, TPA must be administered multiple times for papillomas to form, making both B and C correct.