Which of the Following Types of Mutations are Advantageous to Cancer

Question

Which of the following types of mutations are advantageous to cancer cell growth?
A)Those resulting in defective mismatch repair
B)Inherited defects in double-strand DNA repair
C)A defect in nucleotide-excision repair
D)A,B,and C
E)None of the above

Accepted Answer

Mutations resulting in defective mismatch repair, inherited defects in double-strand DNA repair, and a defect in nucleotide-excision repair are all advantageous to cancer cell growth because they lead to an accumulation of mutations, which can drive the uncontrolled proliferation of cancer cells.