Colony-Stimulating Factor-1 CSF-1)Level 2)

Question

Colony-stimulating factor-1 CSF-1)Level 2)
A)Recruits lymphocytes to tumors.
B)Stimulates the differentiation of monocytes to macrophages.
C)Is involved in tumor initiation.
D)Does not play a role in the development of the tumor stromal compartment.
E)None of the above.

Accepted Answer

CSF-1 stimulates the differentiation of monocytes to macrophages, which play a critical role in the tumor microenvironment by promoting tumor growth and invasion. A and C are incorrect as CSF-1 does not recruit lymphocytes to tumors nor is it involved in tumor initiation. D is incorrect as CSF-1 plays a critical role in the development of the tumor stromal compartment.