Which of the Following Classes of Anti-Cancer Agents Has Been

Question

Which of the following classes of anti-cancer agents has been most successful to date?
A)Low-molecular-weight compounds
B)Antibodies against cancer cells
C)Drugs targeted against receptor-associated tyrosine kinases
D)Antibiotics
E)None of the above

Accepted Answer

Drugs targeted against receptor-associated tyrosine kinases, which are enzymes involved in cell signaling and growth, have been the most successful class of anti-cancer agents to date. Examples include imatinib for chronic myeloid leukemia and trastuzumab for HER2-positive breast cancer. Low-molecular-weight compounds and antibodies against cancer cells have also shown some success, but not to the same extent as drugs targeting tyrosine kinases. Antibiotics are not typically used as anti-cancer agents.