In pancreatic adenocarcinoma,the tumor cells are surrounded by dense stromal tissue,making drug delivery to the cancer cells difficult.Recent studies in mice have shown improved delivery of the drugs gemcitabine and doxorubicin to pancreatic adenocarcinoma cells when concomitantly administered with antagonists of
A)K-Ras. B)p53. C)The Hedgehog signaling pathway. D)PI3K. E)None of the above.