Decreased cytosolic Ca⁺⁺ in smooth muscle typically promotes relaxation by:

A)Closing Ca⁺⁺-activated K⁺ channels in the smooth muscle.
B)Reducing myosin light-chain kinase activity in the smooth muscle.
C)Reducing nitric oxide release from endothelial cells.
D)Reducing Ca⁺⁺ influx through transient receptor potential vanilloid (TRPV)channels in the smooth muscle.
E)Reducing production of inositol 1,4,5-triphosphate (InsP3)in the smooth muscle.