Question 10

(Multiple Choice)

A 25-year-old woman sees her physician because of hirsutism (inappropriate hair growth)and excessive acne.During examination,her blood pressure is 150/90 mm Hg (elevated).Blood work reveals normal Na+ levels but low/normal K+ levels.Testosterone and dihydrotestosterone (DHT)levels are in the high end of the normal range,and the levels of dehydroepiandrosterone sulfate (DHEAS)and adrenocorticotropic hormone (ACTH)are moderately elevated.Her physician suspects late-onset congenital adrenal hyperplasia resulting from subnormal activity of an adrenal enzyme.The subnormal activity of which enzyme explains both the elevated adrenal androgens (e.g.,DHEAS)and hypertension (elevated blood pressure)?


A)CYP11B1
B)CYP17
C)CYP21A2
D)CYP11B2
E)CYP11A1

Answer