One Effect of the Deletion of the HRPB1 Subunit of RNA

Question

One effect of the deletion of the hRPB1 subunit of RNA polymerase II is
A)loss of the oligosaccharide-binding domain.
B)inability of polymerase to bind to transcriptional activators.
C)slowed elongation rate.
D)non-viable cells.
E)extended CTD.

Accepted Answer

The hRPB1 subunit is essential for the function of RNA polymerase II, and its deletion leads to non-viable cells because the enzyme cannot perform its role in transcription, which is critical for cell survival.