One Way to Prevent the Activation of Certain Cells by a Growth

Question

One way to prevent the activation of certain cells by a growth factor is to
A)block phosphorylation of the cytoplasmic domain of the receptor.
B)block dimerization of the receptor.
C)block phosphorylation on the extracellular domain.
D)block phosphorylation of the cytoplasmic domain of the receptor and block dimerization of the receptor.
E)block phosphorylation of the cytoplasmic domain of the receptor and block phosphorylation on the extracellular domain.

Accepted Answer

Blocking both the phosphorylation of the cytoplasmic domain of the receptor and the dimerization of the receptor can prevent the activation of certain cells by a growth factor. Phosphorylation of the cytoplasmic domain is a key step in signal transduction for many growth factor receptors, and dimerization is often required for receptor activation.