How is LTD Generated? Choose All That Apply

Question

How is LTD generated? Choose all that apply. A) High frequency stimulation B) Low frequency stimulation C) Increase in intracellular Ca²⁺ D) Activation of CaMKII

Accepted Answer

Long-term depression is generated by low-frequency stimulation, usually around 1 Hz. CaMKII and increases in Ca²⁺ are involved in LTP.