What are 'Silent Synapses'? Select All That Apply

Question

What are 'silent synapses'? Select all that apply
A) Synapses with no postsynaptic receptors
B) Synapses in which neurotransmitter is not released from the presynaptic neuron
C) Synapses with only NMDARs in their postsynaptic surface
D) Synapses with only AMPARs in their postsynaptic surface
E) Synapses in which AMPARs are inserted into the postsynaptic surface

Accepted Answer

Silent synapses only have NMDARs. The postsynaptic membrane must be depolarized to remove the Mg²⁺ block. If the postsynaptic membrane is depolarized then the Mg²⁺ block will be removed and voltage across the postsynaptic membrane will change when glutamate is released from the presynaptic cell.