What are Presenilins

Question

What are presenilins?
A) Proteins that aggregate in amyloid plaques
B) Proteins that aggregate in neurofibrillary tangles
C) Proteins that are part of the γ-secretase complex
D) One of the cleaved proteins from APP

Accepted Answer

Presenilins are proteins that are part of the γ-secretase complex, which cleaves amyloid precursor protein (APP) into amyloid-beta peptides, a key component in the development of Alzheimer's disease.