What are two Pathological Features of Patients with Alzheimer's Disease

Question

What aretwopathological features of patients with Alzheimer's disease?
A) Death of cells in the substantia nigra
B) Spongiform encephalitis
C) Amyloid plaques
D) Neurofibrillary tangles
E) The presence of Lewy bodies
F) Overexpression of presenilin

Accepted Answer

Two pathological features of Alzheimer's disease are the presence of amyloid plaques, which are formed by the accumulation of beta-amyloid protein in the brain, and neurofibrillary tangles, which are formed by the accumulation of tau protein. Death of cells in the substantia nigra, spongiform encephalitis, the presence of Lewy bodies, and overexpression of presenilin are features that are associated with other neurodegenerative diseases, such as Parkinson's disease, Creutzfeldt-Jakob disease, and Lewy body dementia, and are not specific to Alzheimer's disease.

What are two pathological features of patients with Alzheimer's disease?