If a Tumor Suppressor Gene Becomes Mutated, Which of the Following

Question

If a tumor suppressor gene becomes mutated, which of the following is not true?
A) Apoptosis is less likely to occur.
B) The cell cycle continues when it should not.
C) A "gain-of function" mutation has occurred.
D) Genes that encode enzymes that repair DNA are not turned on.
E) Genes that inhibit the cell cycle are not turned on.

Accepted Answer

A mutation in a tumor suppressor gene typically results in a loss-of-function mutation, not a gain-of-function mutation. This means that the normal inhibitory function of the gene is lost, leading to uncontrolled cell division and potentially, tumor formation.