What Gene is Most Responsible for X-Inactivation

Question

What gene is most responsible for X-inactivation?
A) Xic
B) Xist
C) Tsix
D) Xce

Accepted Answer

Xist (X-inactive specific transcript) is the gene responsible for X-inactivation. It produces a long non-coding RNA which recruits proteins to silence one of the two X-chromosomes in female cells.