The Negatively Charged Ion with the Greatest Concentration in the Blood

Question

The negatively charged ion with the greatest concentration in the blood is
A) protein
B) bicarbonate
C) chloride
D) phosphate

Accepted Answer

Chloride ions (Cl-) are the most abundant negatively charged ions in the blood. They play a critical role in balancing electrical charges between cells, maintaining proper fluid balance, and regulating the pH of the blood. Bicarbonate ions (HCO3-) also play an important role in pH regulation, but their concentration in the blood is lower than that of chloride ions. Protein and phosphate ions have important functions in the body, but their concentration in the blood is much lower than that of chloride ions.