Which of the Following Statements About Initiation of Translation in Bacteria

Question

Which of the following statements about initiation of translation in bacteria is FALSE?
A) fMet-tRNAfMet is the only charged tRNA that can bind to the 30S subunit on its own.
B) The formyl group is transferred to Met-tRNAfMet from 10-formyl-tetrahydrofolate.
C) Three initiation factor proteins are required to bind the mRNA and the initiator tRNA to the 30S ribosome.
D) Pairing between mRNA and rRNA places the initiation codon next to the P site in the ribosome.
E) The complete 70S initiation complex ready to receive a second charged tRNA is assembled without any GTP hydrolysis.

Accepted Answer

The complete 70S initiation complex is not assembled without GTP hydrolysis. GTP hydrolysis by the initiation factors is required for the release of the factors and the formation of the 70S ribosome.