The Greatest Conformational Change in the Neck Piece of Myosin

Question

The greatest conformational change in the neck piece of myosin occurs during ATP hydrolysis.

Accepted Answer

The greatest conformational change in the neck piece of myosin occurs during the release of inorganic phosphate (Pi) from the myosin head after ATP hydrolysis, not during ATP hydrolysis itself. This change is crucial for the power stroke in muscle contraction.