A Genomic DNA Library Is

Question

A genomic DNA library is:
A) a collection of short fragments from nuclear DNA digestion.
B) arrays of synthetic oligonucleotides used to select for a specific DNA.
C) a set of cloned fragments that collectively represent the genes of a particular organism.
D) a short segment of DNA whose sequence is complementary to a portion of the DNA of interest.
E) a circular DNA molecule of 1 kb to 200 kb found in bacteria and yeast cells.

Accepted Answer

A genomic DNA library is a collection of clones containing a representative sample of all the DNA sequences from a particular organism. These clones collectively represent the entire genome of the organism, hence the name "genomic DNA library." Option A is incorrect because short fragments of DNA would not be sufficient to represent the entire genome. Option B describes a different technique called oligonucleotide hybridization. Option D describes a DNA probe used to detect a specific sequence, not a library. Option E describes a plasmid, not a library.