All of the following statements are true about the relationships between [S], K_m and V_max EXCEPT:

A) As the [S] is increased, v approaches the limiting value, V_max.
B) K_m = V_max/2.
C) The rate of the reaction, v, follows a first order rate equation v = K'[A] and K' = V_max/K_m.
D) The rate of product formed, v, is at V_max when [S] >> K_m.
E) K_m and V_max assist in finding the rate of the enzyme catalyzed reaction only if the reaction is irreversible.