All are Characteristic of Allosteric Enzymes EXCEPT

Question

All are characteristic of allosteric enzymes EXCEPT:
A) Effectors may show stimulatory or inhibitory activity.
B) They have multiple subunits.
C) They obey Michaelis-Menten kinetics.
D) The regulatory effect is by altering conformation and interaction of subunits.
E) Binding one subunit impacts binding of substrate to other subunits.

Accepted Answer

Allosteric enzymes do not obey Michaelis-Menten kinetics, as their activity is modulated by the binding of effector molecules to allosteric sites, which can cause conformational changes and either enhance or inhibit the binding of substrate to the active site. This can result in a sigmoidal enzyme kinetic curve instead of the typical hyperbolic curve seen with Michaelis-Menten enzymes. Choices A, B, D, and E are all characteristic of allosteric enzymes.