Self-Assembly of Microtubules Occur By

Question

Self-assembly of microtubules occur by:
A) helical twisting of strands of α-tubulin and β-tubulin.
B) intermolecular interactions of dimers of α-tubulin and β-tubulin.
C) polymerization of alternating α- and β-tubulin into a repeating α-β-α-β-... strand.
D) inter-subunit interaction to form α2β2-tetramers of tubulin.
E) ATP-dependent polymerization of tubulin monomers.

Accepted Answer

Microtubules are composed of dimers of α-tubulin and β-tubulin. The self-assembly occurs by intermolecular interactions between these dimers, which form protofilaments that eventually coil around each other to form the microtubule.