Question 3
(Essay)
Answer
In many infections, certain cytokines released by various cells act on a specific part of the brain to elevate body temperature. In other words, these cytokines stimulate fever. A fever can be a beneficial part of an innate immune response. At elevated body temperature, phagocytic cells are more efficient, and some pathogens are less able to reproduce. Fever, however, is uncomfortable, and is often recognized as one of the symptoms of many diseases. It fever gets too high, it can actually be dangerous or even life-threatening. Thus, while part of a protective immune response, fever, like many aspects of immunity, actually contributes to the symptoms observed during infectious disease.