Which of the Following Explains How an Aminoacyl-TRNA Synthetase (AARS)recognizes

Question

Which of the following explains how an aminoacyl-tRNA synthetase (AARS)recognizes the correct tRNA?
A)the AARS always recognizes the anticodon
B)the AARS always recognizes elements of the acceptor stem
C)the AARS always recognizes the size and sequence in the variable loop
D)the AARS always recognizes elements in the D loop and T$\varPsi$C loop
E)the mechanism of AARS recognition varies from one enzyme to another

Accepted Answer

The mechanism of AARS recognition varies from one enzyme to another. Each AARS recognizes its cognate tRNA through unique mechanisms that involve one or more of the following: recognition of the anticodon, elements of the acceptor stem, size and sequence in the variable loop, or elements in the D loop and TΨC loop. Therefore, there is no universal mechanism that applies to all AARS enzymes.