The reaction of ammonia with $\alpha$ -ketoglutarate is catalyzed by _________ and requires _________ as a reactant.

A)glutamate synthetase;ATP
B)glutamate synthetase;NADH or NADPH
C)glutamate dehydrogenase;ATP
D)glutamate dehydrogenase;NADH or NADPH
E)none of the above