Which of the Following Events Occurs First in the Process

Question

Which of the following events occurs first in the process of transporting an LDL into a cell?
A)formation of a coated pit with the aid of clathrin
B)receptor-mediated endocytosis
C)fusion of the clathrin-lined vesicles to produce an endosome
D)fusion of the cell membrane around the LDL particle
E)interaction of apoprotein B-100 with the LDL receptor

Accepted Answer

The interaction of apoprotein B-100 with the LDL receptor occurs first in the process of transporting an LDL into a cell. This interaction enables the LDL particle to bind to the receptor on the cell membrane, triggering receptor-mediated endocytosis. The other events, such as the formation of coated pits with the aid of clathrin, fusion of the clathrin-lined vesicles to produce an endosome, and fusion of the cell membrane around the LDL particle, occur later in the process.