Which of the Following Functional Groups is a Commonly Seen

Question

Which of the following functional groups is a commonly seen nucleophile in biochemical reactions?
A)aldehyde
B)deprotonated alcohol
C)amide
D)carbocation
E)iodide ion

Accepted Answer

Deprotonated alcohol (also known as an alkoxide ion) is a commonly seen nucleophile in many biochemical reactions, such as in the formation of esters and the cleavage of peptide bonds. It is often generated in situ by treatment of an alcohol with a base, such as hydroxide ion. The other choices are not typically seen as nucleophiles in biochemical reactions.