Which of the following mutations is correctly defined?

A)silent: change of a single base in the non-coding intron region of a gene
B)missense: substitution of a single base results in a premature stop codon
C)nonsense: substitution of a single base results in a complete change of amino acid sequence
D)frameshift: deletion of a single base results in a single amino acid change
E)permissive: results in a protein that has greater thermodynamic stability