RNA Polymerase Can Transcribe in Different Directions on a Chromosome

Question

RNA polymerase can transcribe in different directions on a chromosome.This is enabled because:
A)genes and their associated promoters can be oriented in either direction along a chromosome.
B)RNA polymerase can transcribe from either strand of DNA,synthesizing RNA in the 5′ to 3′ direction.
C)the chemistry of RNA synthesis is identical regardless of which strand is transcribed.
D)the 3′ end of a gene is always the template strand.
E)All of the answer options are correct.

Accepted Answer

All the statements contribute to the ability of RNA polymerase to transcribe in different directions on a chromosome. Genes and promoters can be oriented in either direction (A), RNA polymerase can transcribe from either DNA strand in the 5′ to 3′ direction (B), the chemistry of RNA synthesis does not change based on the strand being transcribed (C), and the orientation of the gene determines which strand serves as the template, not a fixed rule about the 3′ end (D).