Which of the Following Human Diseases is Associated with Balancing

Question

Which of the following human diseases is associated with balancing selection?
A) Tay Sachs
B) Down Syndrome
C) Sickle Cell Anemia
D) Lesch-Nyhan Syndrome
E) Alzheimers Disease

Accepted Answer

Sickle Cell Anemia is associated with balancing selection because the heterozygous carriers (having one normal and one mutated allele) have an advantage in regions where malaria is common. This selective pressure maintains both the normal and mutated alleles in the population.