How Do Cancers Develop

Question

How do cancers develop?
A) Through the activation of a singular proto-oncogene
B) Through the activation of a singular tumor suppressor gene
C) Through the accumulation of somatic mutations in proto-oncogenes and tumor suppressor genes.
D) Through the inactivation of a singular tumor suppressor gene
E) Through the inactivation of a singular proto-oncogene

Accepted Answer

Cancer development involves the accumulation of somatic mutations in proto-oncogenes and tumor suppressor genes, which can lead to the activation of oncogenes and/or the inactivation of tumor suppressor genes. This accumulation of mutations can result from various environmental factors and/or errors in DNA replication or repair mechanisms. Therefore, it is not caused by the activation or inactivation of a singular gene.