What is the Phenotype of Homozygous,loss-Of-Function Mutations in the Sxl

Question

What is the phenotype of homozygous,loss-of-function mutations in the Sxl gene in XY animals?
A) They develop into normal males.
B) They develop into males, but the mutation is lethal.
C) They develop into normal females.
D) They develop into females, but the mutation is lethal.
E) The animals develop as intersexes.

Accepted Answer

In Drosophila, the Sxl gene is involved in sex determination. In XY animals, which are genetically male, a loss-of-function mutation in the Sxl gene does not affect their development into males, as Sxl is not required for male development.