Which of the Following is Found in a YAC

Question

Which of the following is found in a YAC?
A) Yeast origin of replication
B) Two yeast telomeres at the end of the minichromosome
C) Yeast centromere
D) Polylinker site
E) All of these

Accepted Answer

All of these components can be found in a Yeast Artificial Chromosome (YAC). The yeast origin of replication allows the YAC to replicate within yeast cells, the two yeast telomeres at the ends of the minichromosome protect the ends from degradation, the yeast centromere ensures proper segregation during cell division, and the polylinker site allows for insertion of foreign DNA.