Which Statement is Correct About E.coli Promoters

Question

Which statement is correct about E.coli promoters:
A) Most promoters have a high degree of sequence similarity.
B) -10 and -35 regions show the most conservation between promoters.
C) The GC-rich -10 region facilitates the localized unwinding of DNA .
D) Distance between the -10 and -35 regions is moderately conserved from 10 to 30 nucleotides in length
E) None of these statements are correct

Accepted Answer

The -10 and -35 regions are highly conserved between promoters and are recognized by RNA polymerase. The other statements are not entirely accurate- there is some sequence variation among E.coli promoters, the GC-rich -10 region helps stabilize the transcription initiation complex, and the distance between the -10 and -35 regions can vary.