Which DNA Polymerase Molecule Acts as the Replicase in E

Question

Which DNA polymerase molecule acts as the replicase in E.coli?
A) DNA Polymerase I
B) DNA Polymerase II
C) DNA Polymerase III
D) DNA Polymerase IV
E) DNA Polymerase V

Accepted Answer

DNA Polymerase III is the main replicative polymerase in E.coli and is responsible for the bulk of DNA synthesis during replication. It has high processivity, proofreading ability, and synthesizes DNA in the 5' to 3' direction. DNA Polymerase I also participates in DNA replication, but its primary function is in DNA repair and maturation of Okazaki fragments during lagging strand synthesis. DNA Polymerase II, IV, and V are involved in DNA repair, particularly during times of DNA damage or stress.