Which Class of Proteins is Associated with DNA in Chromatin

Question

Which class of proteins is associated with DNA in chromatin?
A) Histones
B) Non-histone chromosomal proteins
C) Enzymes
D) Histones and Non-histone chromosomal proteins
E) All of these

Accepted Answer

Both histones and non-histone chromosomal proteins are associated with DNA in chromatin. Histones are the primary proteins that form the nucleosome structure of chromatin, while non-histone chromosomal proteins have a variety of functions such as regulating gene expression, DNA replication and repair, and higher-order chromatin organization. Enzymes, while important for DNA metabolism, are not typically associated with DNA in chromatin. Therefore, the correct answer is D - Histones and Non-histone chromosomal proteins.