T4 Contains a Modified DNA Base

Question

T4 contains a modified DNA base.Which base is modified and for what purpose?
A) Cytosine; to protect phage DNA from phage encoded DNAse
B) Thymidine; to protect phage DNA from phage encoded DNAse
C) Cytosine; to increase transcription from phage promoters
D) Thymidine; to increase transcription from phage promoters
E) Adenine; to help rupture the bacterial plasma membrane

Accepted Answer

T4 phage DNA contains hydroxymethylcytosine instead of cytosine, which helps protect the phage DNA from degradation by host restriction enzymes.