The Basic Principle in Deletion Mapping is That

Question

The basic principle in deletion mapping is that:
A) A deletion that uncovers a recessive mutation must lack a wild-type copy of the mutant gene
B) A deletion that covers a recessive mutation must lack a wild-type copy of the mutant gene
C) A deletion that uncovers a recessive mutation must contain a wild type copy of the mutant gene
D) A deletion that covers a recessive mutation must contain the recessive mutation of the gene
E) All of these

Accepted Answer

Deletion mapping relies on the principle that a deletion uncovering a recessive mutation indicates the absence of a wild-type allele for that gene within the deletion. This allows for the localization of the gene within the deleted region.