Which of the Following is Required to Unambiguously Link a Gene

Question

Which of the following is required to unambiguously link a gene to a chromosome?
A) The gene must be defined by a mutant allele
B) The chromosome must be morphologically distinguishable
C) The pattern of gene transmission must reflect the chromosome's behavior during reproduction.
D) All of these
E) None of these

Accepted Answer

All three options are required to unambiguously link a gene to a chromosome. Defining the gene by a mutant allele can help narrow down its location, but it is not enough on its own. The chromosome must be identifiable in some way, such as through banding patterns or unique features, to ensure that the gene is actually on that particular chromosome. Finally, the pattern of gene transmission must reflect the behavior of the chromosome during meiosis in order to confirm the linkage. Only when all three of these criteria are met can a gene be confidently linked to a specific chromosome.