Most,but Not All,loss of Function Mutations Can Be Attributed to A

Question

Most,but not all,loss of function mutations can be attributed to a:
A) Dominant allele
B) Recessive allele
C) Codominant allele
D) Partially dominant allele
E) Incompletely dominant allele

Accepted Answer

Loss of function mutations are typically recessive because they require two copies of the mutated allele to result in a phenotype. This means that an individual can carry one mutated allele and one normal allele (known as a carrier) and not show any signs of the mutation, but can still pass it on to their offspring. A dominant allele would result in a phenotype when present in only one copy, which is typically not the case for loss of function mutations. Codominant, partially dominant, and incompletely dominant alleles all involve some degree of expression from both copies of the allele, which is also not typically seen in loss of function mutations.