The Following Structure is Largely Impermeable to Water and Plays

Question

The following structure is largely impermeable to water and plays a role in concentrating urine.  
A) Bowman's capsule
B) Renal medulla
C) Distal tubule
D) Ascending loop of Henle
E) Descending loop of Henle

Accepted Answer

The ascending loop of Henle is largely impermeable to water, which plays a crucial role in the kidney's ability to concentrate urine by allowing for the reabsorption of ions without water following, thus contributing to the creation of a concentration gradient in the renal medulla.