Which Gene Mutation is Least Likely to Impact the Protein

Question

Which gene mutation is least likely to impact the protein?  
A) A conservative substitution
B) A non-conservative substitution
C) An amino acid deletion
D) An amino acid insertion
E) All mutations will have the same impact.

Accepted Answer

A conservative substitution involves replacing one amino acid with another that has similar properties, such as replacing a polar amino acid with another polar amino acid. This is less likely to impact the protein structure and function compared to a non-conservative substitution, amino acid deletion, or insertion.