Which of the Following Nucleotide Changes Leads to a Transition

Question

Which of the following nucleotide changes leads to a transition mutation?
A)Adenine to guanine
B)Adenine to cytosine
C)Guanine to cytosine
D)Thymine to guanine
E)Guanine to thymine

Accepted Answer

A transition mutation involves the substitution of a purine for a purine or a pyrimidine for a pyrimidine. Adenine and guanine are both purines, so changing adenine to guanine is a transition mutation.