Which Immune System(s)are Absent in Individuals with Severe Combined Immunodeficiency

Question

Which immune system(s)are absent in individuals with severe combined immunodeficiency?
A) innate
B) cell-mediated
C) antibody-mediated
D) antibody-mediated and cell-mediated
E) inflammatory response

Accepted Answer

Severe combined immunodeficiency (SCID) is a genetic disorder where both T cells (cell-mediated immunity) and B cells (antibody-mediated immunity) are absent or nonfunctional. Therefore, options C and E are ruled out as they only relate to one type of immunity. Option A is incorrect because innate immunity functions independently of adaptive immunity, and is not affected by SCID. Therefore, the best choice is D.