_____ Corrects the Genetic Defect in an Individual with a Genetic

Question

_____ corrects the genetic defect in an individual with a genetic disorder by _____.
A) Enzyme replacement therapy; delivery of a normal gene to affected cells in the body
B) PGD; removing affected cells from an early stage embryo
C) Gene therapy; PGD
D) Gene therapy; delivery of a normal gene to affected cells in the body
E) Chorionic villus sampling; constructing karyotypes from affected cells

Accepted Answer

Gene therapy is the method of correcting a genetic defect by delivering a normal gene to affected cells in the body. Enzyme replacement therapy can be used for some genetic disorders where the missing or defective enzyme can be supplied, but it does not correct the underlying genetic defect. PGD is a technique used during in vitro fertilization to identify embryos that do not carry a specific genetic mutation, but it does not correct the genetic defect in an affected individual. Chorionic villus sampling is a prenatal diagnostic test that involves taking a sample of placental tissue and analyzing the fetal cells for genetic defects, but it does not correct the genetic defect in an affected individual.