Which of the Following Genes are Expressed Exclusively in Pluripotent

Question

Which of the following genes are expressed exclusively in pluripotent embryonic stem cells?
A)Nanog
B)Sox2
C)Oct4
D)Nanog and Oct4

Accepted Answer

Nanog and Oct4 are known as the main transcription factors that are exclusively expressed in pluripotent embryonic stem cells. Sox2 is also expressed in pluripotent stem cells, but it is also expressed in other cell types. Therefore, the correct answer is D, which includes both Nanog and Oct4.