Proteoglycans Are

Question

Proteoglycans are:
A)located exclusively at the cell surface.
B)located exclusively in the extracellular matrix.
C)highly positively charged.
D)glycoproteins that contain glycosaminoglycans.

Accepted Answer

Proteoglycans are glycoproteins that contain glycosaminoglycans (GAGs). They are found in the extracellular matrix, as well as on the cell surface. Proteoglycans are highly negatively charged due to the presence of GAGs, which are long chains of repeating disaccharides that contain sulfate and/or carboxyl groups.